Keeps you and your baby healthy throughout pregnancy

Replenitol can be safely taken throughout pregnancy to help keep you and your baby well. As it is naturally produced by all people, it is completely safe and has been proven to provide protection against diabetes in pregnancy also known as gestational diabetes (GDM). Three particular studies that examined women at an elevated risk of developing diabetes were assessed in large randomised double-blind trials. The "at-risk" groups were those women with a family history of type 2 diabetes, overweight women with a BMI of 25-30 prior to becoming pregnant and also women who were classified as obese prior to becoming pregnant (BMI above 30). Across all groups, the reduction of risk was reduced by up to 70%. The treatment protocol was identical in each study and required the expectant mothers to take 2 grammes twice daily from the end of the first trimester to delivery.

The main findings are shown in the 3 tables. The first study examined additional parameters and it is interesting to note that babies were not as large compared with the control and there were no abnormally heavy babies. Heavy babies can present challenges to the mother, the baby and the delivery team so preventing what is known as "macrosomia" is an additional, highly desirable benefit.

Gestational diabetes affects 12-18% of women in Ireland and the UK

Keeping well throughout pregnancy is a challenge. The proportion of women who develop diabetes whilst pregnant has dramatically increased recently so action is needed. The challenges to both mother and baby during the very important developmental period can contribute to the risk of needing additional medical intervention for delivery. Furthermore, babies born to mothers who develop gestational diabetes are at an increased risk of developing diabetes themselves. Replenitol is a highly efficacious and cost-effective treatment that lowers the risk of developing GDM by up to 70% and is completely safe to take during pregnancy and breastfeeding. The treatment cost associated with each case of GDM is estimated to be €3-5,000 and the human cost can be inestimable. A preventative course of treatment with Replenitol costs under €190. If you are in an "at-risk" group, you should consider taking Replenitol to keep you and your baby healthy during pregnancy and post-delivery, including whilst breastfeeding.

91.5% reduction among women with elevated fasting blood sugar during the 1st trimester

The 3 studies above show the benefits of treating groups that are at risk and the study table below shows the benefits of treating individuals who have been identified as "at-risk" by assessing fasting blood sugar in the first trimester. At present, individual routine assessment is not part of the standard pregnancy treatment protocols but it may be incorporated in future. The value of individual assessment allows the treatment to be targeted to only those individuals who are at risk but not in an "at-risk" group.

Participants: Non-obese singleton pregnant women with an elevated fasting glucose in the first or early second trimester

Main outcome measure - Development of GDM on a 75g oral glucose tolerance test at 24–28 weeks’ gestation.

71% of the control group developed GDM, compared with just 6% in the treatment group - a 91.5% reduction